![](http://formulations.in/Products/JAZOPANT-40.jpg)
Composition
- Each tablet contains:
- Pantoprazole 40 mg
Packing
- 10x15
Alu-Alu
MRP
- 148
Overview
Pantoprazole is known as acid neutralizing drug and is classified under proton pump inhibitors. it helps to neutralize the excess of acid in the stomach. It is used to treat reflux esophagitis
Indications
- Esophagitis
- Gastroesophageal reflux disease
- Zollinger-elision syndrome
- Peptic ulcers
- Duodenal ulcers
Mechanism of Action
Pantoprazole works by binding with the H+K+ATPase pump on the parietal cells and neutralize the excess of acid produced in the stomach.
Pharmacokinetics
Absorption:
It is absorbed orally
Protein binding:
It is 98% bound to plasma proteins
Metabolism:
It is metabolized in the liver
Excretion:
It is excreted via urine
Side Effects
- Nausea
- Fever
- Confusion
- Bloating
- Increased blood pressure
Contraindication
- Contraindicated in systemic lupus erythematosus
- Contraindicated in autoimmune disease
Drug Interaction
- Nelfinavir
- Warfarin
- Ketoconazole
- Iron salts
- Mycophenolate mofetil