CTRIJEEN Tablets

Composition
  • Each film coated tablet contains:
  • Cetirizine HCL IP 10 mg
Packing
  • 12X5X10
    Blister
MRP
  • 18.48

Overview

Cetirizine belongs to the class of second-generation antihistaminic drugs and is used in the treatment of allergic reactions such as sneezing, coughing, nasal congestion or hives. It is also used in asthma and it improves the urticaria condition such as wheel and flare. Its action is due to its metabolite hydroxyzine.

Indications

  • Seasonal allergic rhinitis
  • Perennial allergic rhinitis
  • Chronic urticaria
  • Respiratory allergy
  • Pollen allergy

Mechanism of Action

Cetirizine selectively inhibit the histamine receptor i.e. H1 located on the periphery and thus it blocks its activity.

Pharmacokinetics

Absorption: It is absorbed orally
Protein Binding: It is 93% bound to plasma proteins
Metabolism: It undergoes oxidative-N-dealkylation
Excretion: It is excreted unchanged via urine

Side Effects

  • Diarrhoea
  • Sore throat
  • Sick
  • Stomach pain
  • Headaches
  • Dizziness
  • Tiredness

Contraindication

  • Contraindicated in people with known hypersensitivity

Drug Interaction

  • Ibuprofen
  • Loratadine
  • Phenylepinephrine
  • Prednisone