Composition

• Each uncoated tablet contains:
• Cinnarizine IP 25 mg

Packing

• 10x25
  Blister
  

MRP

• 181

Overview

Cinnarizine belongs to the category of antihistaminic drug and is usually used in the treatment of motion sickness. It has sedating effect and it produces sleep more than that of any other antihistaminic drugs produces. It is also indicated to treat nausea and vomiting.

Indications

• Treat vertigo
• Nausea
• Vomiting
• Motion sickness

Mechanism of Action

Cinnarizine inhibits the L-type and T-type voltage gated calcium channels and thus inhibits the contractions of smooth muscles. It does not bind with other neurotransmitters such as dopamine d2, H1, muscarinic receptors.

Pharmacokinetics

It is absorbed orally

Side Effects

• Drowsiness
• Sweating
• Dry mouth
• Headache
• Skin problems
• Lethargy

Contraindication

• Contraindicated in people with known hypersensitivity
• Contraindicated in Parkinson’s disease
• Contraindicated in depression